Abstract #4606

Dynamic O2-Enhanced MRI Vs. Quantitative Thin-Section MDCT: Capability for COPD Assessment in Smokers

Yoshiharu Ohno^1,2, Hisanobu Koyama¹, Keiko Matsumoto^1,3, Yumiko Onishi¹, Daisuke Takenaka¹, Munebu Nogami¹, Nobukazu Aoyama², Hideaki Kawamitsu², Makoto Obara⁴, Marc van Cauteren⁴, Kazuro Sugimura¹

¹Radiology, Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan; ²Radiology, Kobe University Hospital, Kobe, Hyogo, Japan; ³Radiology, Yamanashi University, Shimokatou, Yamanashi, Japan; ⁴Philips Healthcare, Tokyo, Japan

Direct assessment of signal intensity - time course curve on dynamic O2-enhanced MRI have suggested as having potential for airway abnormality and oxygen transfer assessments. However, the literature shows no publications dealing with direct comparison of the capability of quantitatively assessed thin-section MDCT and of dynamic O2-enhanced MRI for COPD assessment in smokers. We hypothesized that dynamic O2-enhanced MRI may have potential for COPD assessment, and be considered at least as valuable as MDCT in smokers. The purpose of this study was to compare the capability for COPD assessment in smokers between dynamic O2-enhanced MRI and quantitatively assessed thin-section MDCT.