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Abstract #4606

Dynamic O2-Enhanced MRI Vs. Quantitative Thin-Section MDCT: Capability for COPD Assessment in Smokers

Yoshiharu Ohno1,2, Hisanobu Koyama1, Keiko Matsumoto1,3, Yumiko Onishi1, Daisuke Takenaka1, Munebu Nogami1, Nobukazu Aoyama2, Hideaki Kawamitsu2, Makoto Obara4, Marc van Cauteren4, Kazuro Sugimura1

1Radiology, Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan; 2Radiology, Kobe University Hospital, Kobe, Hyogo, Japan; 3Radiology, Yamanashi University, Shimokatou, Yamanashi, Japan; 4Philips Healthcare, Tokyo, Japan

Direct assessment of signal intensity - time course curve on dynamic O2-enhanced MRI have suggested as having potential for airway abnormality and oxygen transfer assessments. However, the literature shows no publications dealing with direct comparison of the capability of quantitatively assessed thin-section MDCT and of dynamic O2-enhanced MRI for COPD assessment in smokers. We hypothesized that dynamic O2-enhanced MRI may have potential for COPD assessment, and be considered at least as valuable as MDCT in smokers. The purpose of this study was to compare the capability for COPD assessment in smokers between dynamic O2-enhanced MRI and quantitatively assessed thin-section MDCT.