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Abstract #4645

Contribution of Phase-Contrast Magnetic Resonance Imaging in the Study of Hepatic Fibrosis: Preliminary Results

Thierry Yzet1, Roger Bouzerar2, Eric Nguyen-Khac3, Brice Robert1, Denis Chatelain4, Herv Deramond1, Marc-Etienne Meyer2, Olivier Baledent2

1Radiology, University Hospital, Amiens, France; 2Imaging and Biophysics, University Hospital, Amiens, France; 3Hepato-Gastroenterology, University Hospital, Amiens, France; 4Pathological Cytology, University Hospital, Amiens, France


Hepatic fibrosis is secondary to many etiologies and quantification of this fibrosis is a key point for the clinician. In this work, we wanted to appraise the potential links between elastometry data and parameters measured using PC-MRI in 17 subjects developing hepatic pathologies. Three distinct groups, probably representative of the stage of hepatic fibrosis, clearly appear A statistically significant linear correlation between the elasticity modulus and the vessel area variations DS or the portal congestion index IC is clearly highlighted. PC-MRI could be a useful and complementary tool for the understanding of evolution mechanisms involved in hepatic fibrosis.

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