Renal Angiomyolipoma Fat Content Estimated on Pretreatment MRI as a Predictor of Response to Embolization

Joseph Abrams¹, Timothy W. Clark¹, Rahmin A. Rabenou², Hersh Chandarana¹

Transarterial embolization prevents hemorrhage of renal angiomyolipoma (AML) by decreasing the tumors angiogenic component. Our aim was to determine whether baseline AML lipid content, as estimated by AML-to-psoas signal ratio on T1 fat-saturated non-contrast acquisition, could help predict embolization response, as measured by changes in volume and enhancement on gadolinium contrast enhanced MRI (CE-MRI). Moderately good correlations were seen between baseline lipid content and change in volume and change in enhancement. These results suggest that AMLs with higher fatty components, as determined on MRI, are less likely to respond to embolization.