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Abstract #4693

Renal Blood Flow Changes in Autosomal-Dominant Polycystic Kidney Disease

Wei Zhang1, Jon D. Blumenfeld2, Stephanie Donahue2, Honglei Zhang1, Martin R. Prince1

1Radiology, Weill Cornell Medical College, new york, NY, United States; 2Internal Medicine, Weill Cornell Medical Center and The Rogosin Institute, new york, NY, United States

Purpose: To assess how renal blood flow changes in autosomal-dominant polycystic kidney disease (ADPKD) and its correlation with renal parenchymal volume and function.Methods: 41 ADPKD patients underwent MRA of the renal arteries using 2D cine Phase Contrast besides routine abdominal MRI.Results: GFR to both kidneys correlated directly with total blood flow.Conclusion:Our research suggest that measuring total flow to bilateral kidneys may represent an effective way to monitor renal function in ADPKD patients.