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Abstract #4703

Contrast Edited T2 SSFSE: A Potential Alternative to Diffusion Weighted EPI for MRI Screening

Ananth J. Madhuranthakam1, Aya Yassin2,3, Jean H. Brittain4, David C. Alsop2,3, Neil M. Rofsky2,3

1MR Applied Science Lab, GE Healthcare, Boston, MA, United States; 2Radiology, Beth Israel Deaconess Medical Center, Boston, MA, United States; 3Harvard Medical School, Boston, MA, United States; 4MR Applied Science Lab, GE Healthcare, Madison, WI, United States

MRI has gained increased attention for whole-body screening of tumor metastasis. The commonly used sequences are STIR and DW-EPI. However, both are SNR limited and require multiple signal averages increasing the total scan time. In addition, DW-EPI images are also subject to distortion in larger FOVs, and are typically limited to low resolution, axial plane imaging. The primary objective of whole-body screening is to minimize the background tissue signal while simultaneously highlighting tumor signal in a rapid acquisition. Such a technique is presented in this work using SSFSE readout while suppressing signal from fat, fluid and blood vessels.