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Abstract #4704

Assessing the Advantages of Whole Body Diffusion Tensor Imaging for Screening of Bone Metastases

Matthew David Blackledge1, David J. Collins1, Toni Wallace1, Dow-Mu Koh1, Martin O. Leach1

1CR-UK and EPSRC Cancer Imaging Centre, Institute of Cancer Research and Royal Marsden Hospital, Sutton, Surrey, United Kingdom

We have demonstrated that the use of whole body DTI is feasible and practicable in the time required to obtain standard diffusion weighted whole body measurements of bone metastases without significant loss in image quality. Furthermore it is possible to measure useful biological parameters such as fractional anisotropy which may have direct clinical relevance in detecting spinal cord compression.