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Abstract #4708

Comparison of Liver ADC Measurements Using Breath-Hold, Free Breath-Hold and Respiratory Gating Echoplanar Diffusion-Weighted Imaging Sequences Using Parallel Imaging Technique with Different Acceleration Factors

Chun-Jung Juan1, Hing-Chiu Chang2,3, Hsiao-Wen Chung1,3, Chi-Hong Chu4, Cheng-Chieh Cheng1,3, Su-Chin Chiu1,3, Hui-Chu Chiu5,6, Cheng-Hsien Hsu7, Cheng-Yu Chen1, Guo-Shu Huang1

1Department of Radiology, Tri-Service General Hospital, Taipei, Taiwan; 2Applied Science Laboratory, GE Healthcare Taiwan, Taipei, Taiwan; 3Institute of Biomedical Electronics and Bioinformatics, National Taiwan University, Taipei, Taiwan; 4Section of General Surgery, Department of Surgery, Tri-Service General Hospital, Taipei, Taiwan; 5Department of Nuclear Medicine, Tri-Service General Hospital, Taipei, Taiwan; 6EMBA in Global Chinese Management, Department of Business Administration, College of Management, Tamkang University, Taiwan; 7Division of Software Design, Notebook Unit 5, Quanta Computer Inc., Taiwan

Inter-experimental comparison of the liver apparent diffusion coefficient (ADC) value remains challenging. In this study the effect of repetition time (TR) and acceleration factors on the liver ADC measurement is examined. Our study shows that free-breath method allows ADC measurement consistent with breath-hold method with the TR. The ADC values measured at a longer TR in both free-breath and respiration-triggered methods are significantly higher than breath-hold method. Our results also depict significant differences in liver ADC values when different acceleration factors are chosen. Our results highlight the important of TR and acceleration factors in liver ADC measurements for inter-experimental comparison.