Chun-Jung Juan1, Hing-Chiu Chang2,3,
Hsiao-Wen Chung1,3, Chi-Hong Chu4, Cheng-Chieh Cheng1,3,
Su-Chin Chiu1,3, Hui-Chu Chiu5,6, Cheng-Hsien Hsu7,
Cheng-Yu Chen1, Guo-Shu Huang1
1Department of Radiology, Tri-Service
General Hospital, Taipei, Taiwan; 2Applied Science Laboratory, GE
Healthcare Taiwan, Taipei, Taiwan; 3Institute of Biomedical
Electronics and Bioinformatics, National Taiwan University, Taipei, Taiwan; 4Section
of General Surgery, Department of Surgery, Tri-Service General Hospital,
Taipei, Taiwan; 5Department of Nuclear Medicine, Tri-Service
General Hospital, Taipei, Taiwan; 6EMBA in Global Chinese
Management, Department of Business Administration, College of Management,
Tamkang University, Taiwan; 7Division of Software Design, Notebook
Unit 5, Quanta Computer Inc., Taiwan
Inter-experimental
comparison of the liver apparent diffusion coefficient (ADC) value remains
challenging. In this study the effect of repetition time (TR) and
acceleration factors on the liver ADC measurement is examined. Our study
shows that free-breath method allows ADC measurement consistent with
breath-hold method with the TR. The ADC values measured at a longer TR in
both free-breath and respiration-triggered methods are significantly higher
than breath-hold method. Our results also depict significant differences in
liver ADC values when different acceleration factors are chosen. Our results
highlight the important of TR and acceleration factors in liver ADC
measurements for inter-experimental comparison.