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Abstract #4715

Diffusion Weighted Imaging in Differentiating Malignant from Benign Intraductal Papillary-Mucinous Neoplasm of the Pancreas

Atsushi Nakamoto1, Tonsok Kim1, Masatoshi Hori1, Hiromitsu Onishi1, Takahiro Tsuboyama1, Mitsuaki Tatsumi1, Noboru Maeda1, Hiroki Higashihara1, Keigo Osuga1, Kaname Tomoda1

1Department of Radiology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan


We retrospectively evaluated the diagnostic performance of diffusion-weighted imaging (DWI) and apparent diffusion coefficient (ADC) value for differentiating malignant intraductal papillary-mucinous neoplasm (IPMN) of the pancreas from benign IPMN. The mean minimum ADC value of malignant IPMN was lower than that of benign IPMN (P < 0.001). Mean Az value, sensitivity, specificity and accuracy of MR imaging with DWI were higher than those of MR imaging without DWI, although differences were not significant. We conclude that DWI and measurement of minimum ADC value would be helpful for differentiating malignant IPMN form benign IPMN.