Meeting Banner
Abstract #4723

Effect of Nutritional State on IVIM Parameters Measured with Multiple B Value Diffusion MRI

Clifford R. Weiss1, Atilla Peter Kiraly2, Ralph Strecker3

1Department of Radiology, The Johns Hopkins Univeristy School of Medicine, Baltimore, MD, United States; 2Imaging and Visualization, Siemens Corporate Research, Princeton, NJ, United States; 3MR Oncology, Siemens Healthcare, Erlangen, Germany

Existing liver diffusion MR studies have moderate variability in computed ADC values. Reasons from transient changes in portal venous flow to noise have been attributed to this variability. However, the massive increase in splanchnic/portal blood flow after eating does not seem to be taken into account. We present a study comparing diffusion data before and after fasting that shows a large increase in ADC values after eating. Although it is a small study, results suggest that patient feeding state should be factored into future studies.