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Abstract #4769

Effect of External Beam Radiotherapy on Prostate ADC Values

Daniel Wilson1, Sarah Bacon1, Brendan Carey2

1Medical Physics, Leeds Teaching Hospitals NHS Trust, Leeds, West Yorkshire, United Kingdom; 2Radiology, Leeds Teaching Hospitals NHS Trust, Leeds, West Yorkshire, United Kingdom


Prostate ADC values were calculated using a variety of b-value combinations from b=0, 50, 300 and 500 s/mm2. The calculated ADC depended on the combination of b-values used. All combinations showed a decrease in ADC post radiotherapy compared to pre radiotherapy. This difference was statistically significant for all combinations except b=300 and 500 s/mm2 combined. This decrease in ADC may be a result of radiation induced cellular changes.

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