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Abstract #4785

Fast T2 Relaxometry in Prostate Cancer Patients at 3T

Wei Liu1, Julien Senegas2, Baris Turkbey3, Dagane Daar4, Marcelino Bernardo4, Peter Choyke3

1Clinical Sites Research Program, Philips Research North America, Briarcliff Manor, NY, United States; 2Sector of Tomographic Imaging, Philips Research Europe, Hamburg, Germany; 3Molecular Imaging Program, National Cancer Institute, Bethesda, MD, United States; 4Molecular Imaging Program, National Cancer Institute, SAIC-Frederick Inc., Bethesda, MD, United States

A fast T2 mapping technique using multi-echo spin-echo sequence with four-fold undersampling has been applied to characterize prostate T2 values in 23 patients. Utilizing the temporal and spatial correlation of T2 signal decay, folding-free images were reconstructed at each echo time providing a series of diagnostic images with variable T2-weighting. Quantitative T2 maps were generated with very good reproducibility in clinical relevant scan time. T2 values of tumor tissues were significantly lower than the normal control regions. Our results demonstrate this fast T2 relaxometry can provide an effective approach for accelerated T2 quantification in prostate patients.