Christina Louise Tosti1, Haiying Tang2,
Srirama V. Swaminathan3, Sujit S. Sheth2, Jens H.
Jensen4, Alvaro Nunez4, Kristi Hultman5,
Daniel Kim4, Ed X. Wu6, Gary M. Brittenham2,
Truman R. Brown2
1The Ohio State University, Columbus,
OH, United States; 2Columbia University, New York, NY, United
States; 3Philips Healthcare, Andover, MA, United States; 4New
York University, New York, NY, United States; 5Mayo Clinic,
Rochester, MN, United States; 6The University of Hong Kong, Hong
Kong, Hong Kong
Phantoms
that simulate the iron in tissue have been measured using a theoretical model
that can separately quantify dispersed (ferritin-like) and aggregated
(hemosiderin-like) iron using multiple spin echo (MSE) based R2 images. Here,
we examine a large range of these heterogeneous phantoms and a preliminary
patient population to determine the effects of stimulated echo (STE)
contamination in MSE sequences on the iron quantification.