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Abstract #4980

Influence of Stimulated Echoes on Iron Quantification with Multi-Echo Spin-Echo Pulse Sequences

Christina Louise Tosti1, Haiying Tang2, Srirama V. Swaminathan3, Sujit S. Sheth2, Jens H. Jensen4, Alvaro Nunez4, Kristi Hultman5, Daniel Kim4, Ed X. Wu6, Gary M. Brittenham2, Truman R. Brown2

1The Ohio State University, Columbus, OH, United States; 2Columbia University, New York, NY, United States; 3Philips Healthcare, Andover, MA, United States; 4New York University, New York, NY, United States; 5Mayo Clinic, Rochester, MN, United States; 6The University of Hong Kong, Hong Kong, Hong Kong

Phantoms that simulate the iron in tissue have been measured using a theoretical model that can separately quantify dispersed (ferritin-like) and aggregated (hemosiderin-like) iron using multiple spin echo (MSE) based R2 images. Here, we examine a large range of these heterogeneous phantoms and a preliminary patient population to determine the effects of stimulated echo (STE) contamination in MSE sequences on the iron quantification.