Vincenzo
Positano1, Luca Menichetti1, Alessia Pepe1,
Antonella Meloni1, Daniele De Marchi1, Matteo Milanesi1,
Maria Filomena Santarelli1, Giovanni Palazzi2, Massimo
Lombardi1, Luigi Landini1,3
1MRI
Lab, "G. Monasterio" Foundation and Institute of Clinical
Physiology, Pisa, Italy; 2Oncoematologia Pediatrica, Policlinico
di Modena, Modena, Italy; 3Department of Information Engineering,
University of Pisa, Pisa, Italy
T2*
multiecho magnetic resonance is an established methodology for assessment of
iron overload in heart, liver, and other organs by evaluation of the T2*
value. However, the dependence of the expected error from T2* value and
acquisition parameters is unknown. This study demonstrate that evaluation of
Cramer-Rao lower bounds allows to quantify the precision limits of T2*
assessment for various schema of TEs. CRLB approach was applied to evaluate
the T2* measurement quality in thalassemia patients.
Keywords