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Abstract #4989

Rapid T1 Determination with Optimized Inversion Recovery Sequence

Ke Li1,2, Junzhong Xu1,2, Zhongliang Zu1,2, John C. Gore1,2, Mark D. Does1,2, Daniel F. Gochberg1,2

1Vanderbilt University Institute of Imaging Science, Nashville, TN, United States; 2Department of Radiology and Radiological Sciences, Vanderbilt University, Nashville, TN, United States

In this work, the inversion recovery sequence was optimized for T1 measurements, by varying both the inversion recovery time (ti) and pre-delay (td). Comparing to conventional acquisition scheme, which uses logarithmic spacing ti and long td (> 5T1), the optimized sequence has precision efficiency of ~ 2.5 times greater than the conventional scheme.