Abstract #5003

Resolving Phase: Inversion of SWI-Phase Data in Order to Obtain Its Sources Utilizing the Concept of a Generalized Lorentzian Approximation

Ferdinand Schweser¹, Moritz Htten², Berengar Wendel Lehr², Andreas Deistung², Daniel Gllmar², Jrgen Rainer Reichenbach²

¹Medical Physics Group, Department of Diagnostic and Interventional Radiology , Jena University Hospital, Jena, Germany; ²Medical Physics Group, Department of Diagnostic and Interventional Radiology, Jena University Hospital, Jena, Germany

Phase data acquired at multiple orientations with respect to the magnetic field was inverted to susceptibility, rotation-invariant local shift, and anisotropy-related susceptibility. Results indicate that gray-to-white matter contrast in phase images is dominated by sources from magnetic susceptibilities rather than macro-molecular exchange processes.