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Abstract #5033

PROspective MOtion Correction (PROMO) Results in Improved Image and Segmentation Quality of High-Resolution MRI Scans of Children

Joshua M. Kuperman1,2, Timothy T. Brown, 23, Matthew J. Erhart, 23, J Cooper Roddey, 23, Nathan Cooper White, 2,4, Ajit Shankaranarayanan5, Eric T. Han5, Daniel Rettmann6, Anders M. Dale, 23

1Radiology, UCSD, La Jolla, CA, United States; 2Multimodal Imaging Lab, UCSD, La Jolla, CA, United States; 3Neurosciences, UCSD, La Jolla, CA, United States; 4Cognitive Science, UCSD, La Jolla, CA, United States; 5Applied Science Lab, GE Healthcare, Menlo Park, CA, United States; 6Applied Science Lab, GE Healthcare, Rochester, MN, United States

In order to test the utility of PROspective MOtion correction (PROMO) for pediatric MRI research, nine children, ages 9-12, were scanned four times with a high-resolution T1-weighted sequence. For each subject, PROMO on and off scans were collected in a counterbalanced alternating pattern. Results show a qualitative enhancement in image clarity and reduction of apparent motion artifacts with the use of PROMO. Furthermore, automated segmentations of PROMO-enabled images show significant improvements in quality and reliability as compared to PROMO-off images. Volumetric segmentations of structures show consistently greater percent volume overlap when PROMO is enabled.