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Abstract #0214

Adenosine-Induced Stress Myocardial Perfusion MRI using SW-CG-HYPR with Whole Left Ventricular Coverage: Comparison of Results with X-Ray Angiography in Patients with Suspected Coronary Artery Disease

Heng Ma1, Lan Ge2, Jing An3, David Chen2, Lixin Jin4, Xiaoming Bi5, Renate Jerecic4, Kuncheng Li1, Debiao Li2,6

1Xuanwu Hospital, Capital Medical University, Beijing, China, People's Republic of; 2Northwestern University; 3Siemens Healthcare, MR Collaboration NE Asia, Siemens Mindit Magnetic Resonance; 4Siemens Healthcare, MR Collaboration NE Asia, Siemens Limited China; 5Siemens Healthcare, Cardiovascular MR R&D, USA; 6Cedars-Sinai Medical Center & UCLA


Myocardial perfusion MRI with SW-CG-HYPR allows increased spatial coverage (whole left ventricular coverage), resolution, signal-to-noise ratio and reduced motion artifacts. The accuracy of this technique for detecting CAD has not been determined in a large number of patients. In this work, we have prospectively examined the diagnostic value of adenosine-induced stress myocardial perfusion MRI using SW-CG-HYPR in 50 patients with suspected CAD. Using the SW-CG-HYPR method, perfusion MRI was able to cover the whole left ventricle with an accuracy of 90% and 93% based on per-patient and per-vessel analyses, respectively, using X-ray coronary angiography as a reference standard.