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Abstract #0232

Is Iron the Source of Post Mortem Susceptibility Contrast in the Brain?

Ferdinand Schweser1,2, Christian Langkammer3,4, Andreas Deistung1, Nikolaus Krebs4, Walter Goessler5, E. Scheurer4, K. Yen4, Franz Fazekas3, Jrgen R. Reichenbach1, Stefan Ropele3

1Medical Physics Group, Dept. of Diagnostic & Interventional Radiology 1, Jena University Hospital, Jena, Germany; 2School of Medicine, Friedrich Schiller University of Jena, Jena, Germany; 3Dept. of Neurology, Medical University of Graz, Graz, Austria; 4Ludwig Boltzmann Institute for Clinical-Forensic Imaging, Graz, Austria; 5Institute of Chemistry, Analytical Chemistry, University of Graz, Graz, Austria

Quantitative information of the regional non-heme tissue iron distribution bears clinical potential in the context of various neurological and psychiatric disorders. The goal of the current study was to investigate and compare the relation between tissue iron concentration and tissue magnetic susceptibility of in situ and fixed post mortem brain tissue.