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Abstract #0305

Elucidating Brain Metabolism by Dynamic 13C Isotopomer Analysis

Alexander A. Shestov1, Dinesh K. Deelchand1, Kamil Ugurbil1, Pierre-Gilles Henry1

1Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, MN, USA

Information from 13C isotopomers, which appear as multiplets in 13C NMR spectra can be measured and quantified in vivo. We show here that using this additional information on isotopomers along with an extended brain bionetwork model allows accurate fitting of the experimental dynamic 13C isotopomer turnover curves.