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Abstract #0467

Carotid Atherosclerotic Lesion Distribution in Patients with Cerebrovascular Events: A 3.0 Tesla Magnetic Resonance Vessel Wall Imaging Study using Three-dimensional, Isotropic, Fast Sequence with Large Coverage

Xihai Zhao1, Niranjan Balu2, Jinnan Wang3, Huilin Zhao4, Jianrong Xu4, Chun Yuan1,2

1Department of Biomedical Engineering & Center for Biomedical Imaging Research, School of Medicine, Tsinghua University, Beijing, China, People's Republic of; 2Department of Radiology, University of Washington, Seattle, WA, USA; 3Philips Research North America, Briarcliff Manor, NY, USA; 4Department of Radiology, Renji Hospital, Shanghai Jiao Tong University, Shanghai, China, People's Republic of

Multicontrast vessel wall imaging has been widely used for characterizing carotid atherosclerosis. However, this imaging protocol could not assess the full spectrum of carotid atherosclerotic lesion distribution due to its limited longitudinal coverage (40 mm). Recently, 3D fast sequence MERGE with isotropic resolution, large-coverage (> 80 mm) and short-scan-time (2 min) is emerging as a promising approach for identification of carotid plaques. In this study, we used 3D MERGE sequence to determine carotid lesion distribution and found that near one fourth of lesions occurred in proximal common carotid artery which is beyond the imaging coverage of current multicontrast protocol.