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Abstract #0528

Feasibility of Temperature Imaging of Fat & Water Based on Methylene T1 & Water Proton Resonance Frequency

Kagayaki Kuroda1,2, Mie Kee Lam3, Taku Iwabuchi1, Makoto Obara4, Masatoshi Honda5, Kensuke Saito1, Yutaka Imai5

1Graduate School of Engineering, Tokai University, Hiratsuka, Kanagawa, Japan; 2Medical Device Development Center, Foundation for Biomedical Research & Innovation, Kobe, Hyogo, Japan; 3Image Sciences Institute, University Medical Center Utrecht, Utrecht, Netherlands; 4MR Marketing, Philips Electronics Japan Medical Systems, Shinagawa, Tokyo, Japan; 5Department of Radiology, Tokai University, Isehara, Kanagawa, Japan

Based on the temperature dependence of T1 of methylene (CH2) or methyl (CH3) protons, we have proposed a temperature imaging technique using multiple flip angle, multipoint Dixon acquisitions and a least square estimation. This technique can be combined with the water temperature imaging technique based on the proton resonance frequency (PRF) shift, because the intra-voxel signal fractions of water and fat protons can be obtained once the proton components are separated. In this paper, feasibility of such an integrated temperature imaging technique is demonstrated with phantom experiments at 3T.