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Abstract #0537

Orthogonal Super Resolution Reconstruction for 3D Isotropic Imaging in 9.4T MRI

Niranchana Manivannan1, Bradley D. Clymer1, Anna Bratasz2,3, Kimerly A. Powell2,3

1Department of Electrical & Computer Engineering, The Ohio State University, Columbus, OH, USA; 2Small Animal Imaging Shared Resource, The Ohio State University; 3Department of Biomedical Informatics, The Ohio State University, Columbus, OH, USA

The goal of this research is to apply orthogonal super resolution (SR) reconstruction technique to create isotropic 3D MRI images from 2D multislice stacks of images. The evaluation of this technique was performed in ex-vivo mouse model where the results of the SR reconstruction were quantitatively and qualitatively compared to an isotropically acquired 3D image . The structural detail observed in the through-plane direction of the SR reconstructed images was comparable to that observed in the isotropically acquired 3D scans. For the first time SR algorithm is successfully used to reconstruct in-vivo 3D isotropic volume in Ultra high field MRI.