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Abstract #0572

Ultrashort TE Spectroscopic Imaging (UTESI): An Efficient Technique For Free & Bound Water Quantification

Jiang Du1, Eric Diaz1, Richard Znamirowski1, Sheronda Statum1, Darryl DLima2, Graeme Bydder1, Christine Chung1

1Radiology, University of California, San Diego, San Diego, CA, USA; 2Scripps Reseach Institution

It is well accepted that biological tissues commonly contain distinct water compartments and display two or more T2 components. However, conventional T2 relaxometry still focuses on single component analysis using multi-echo spin echo sequences, which typically cannot detect signal from the short T2 components in a variety of musculoskeletal (MSK) tissues. Here we propose a bi-component T2* analysis of images from ultrashort TE spectroscopic imaging (UTESI) sequence to quantify T2* and fractions of the free and bound water components in a series of MSK tissues.