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Abstract #0629

Results on Rapid 3D Magnetic Particle Imaging with a Large Field of View

Jrgen Rahmer1, Bernhard Gleich1, Claas Bontus1, Ingo Schmale1, Joachim Schmidt1, Jrgen Kanzenbach1, Oliver Woywode2, Jrgen Weizenecker3, Jrn Borgert1

1Philips Research Laboratories, Hamburg, Germany; 2Philips Medical Systems DMC GmbH, Hamburg, Germany; 3University of Applied Sciences, Karlsruhe, Germany

Magnetic particle imaging (MPI) is a new tomographic imaging approach that quantitatively maps concentrations of iron oxide nanoparticle distributions. It combines high sensitivity with the ability of fast volumetric imaging. Previously, in vivo 3D real-time MPI of a bolus of particles flowing through the heart and lung of mice has been demonstrated, but with an imaging approach that is limited to small fields of view (FoVs). Recently, a new scanner type with a bore diameter of 12 cm allowing rapid imaging with enlarged FoVs has been developed. This contribution describes the sequences used for imaging of large FoVs and presents initial phantom results acquired on the new system.