Inter-Subject Variability of Structural Network: A DTI Study

Hu Cheng¹, Jinhua Sheng², Yang Wang², Olaf Sporns¹, Andrew Saykin², William Kronenberger², Vincent Mathews², Thomas Hummer²

Structural network was constructed based DTI tractography and FreeSurfer parcellation on fifty six young normal male subjects. Various network analyses were applied to examine the feature of the backbone network as well as inter-subject variations. The result shows that the backbone network can be clustered into four modules. Although some global measures of the network are less fluctuated, the pattern of local connectivity may vary dramatically from subject to subject.