Abstract #0711

Examining the Accuracy of Dual Echo B0 Map for Field Inhomogeneity Correction with the Application of gagCEST in Articular Cartilage at 3T

Wenbo Wei¹, Guang Jia¹, David C. Flanigan², Christopher C. Kaeding², Jinyuan Zhou³, Steffen Sammet¹, Peter Arjan Wassenaar¹, Michael V. Knopp¹

¹Wright Center of Innovation in Biomedical Imaging & Department of Radiology, The Ohio State University, Columbus, OH, USA; ²Department of Orthopedics, The Ohio State University, Columbus, OH, USA; ³Department of Radiology, Johns Hopkins University, Baltimore, MD, USA

With a better B₀ map acquisition in gagCEST imaging, an entire CEST spectrum is not necessary and total scan time can be reduced. In this study, B₀ inhomogeneity correction using the dual echo B₀ map with different δTEs was performed to compare to the minimum point correction in gagCEST imaging of clinical knee patients. It shows that with proper δTE B₀ maps we are able to make reliable B₀ inhomogeneity corrections to CEST spectra which enables gagCEST to be more feasible for clinical use.