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Abstract #0803

Evaluation of Individual Versus Average T2* Decay Correction & Single Slice Versus Multislice Sampling in the Two-Point Dixon Method for Liver Fat Quantification

Cemil Kirbas1, Eric Zalusky1, Stefan Czerwinski2, Miryoung Lee2, Ke Cheng Liu3, Jason G. Parker1

1Innovation Center, Kettering Health Network, Kettering, OH, United States; 2Department of Community Health, Wright State University, Kettering, OH, United States; 3Siemens Medical Solutions, United States

Assessment of fat content in the liver is of interest in the evaluation of a spectrum of diseases. Quantification of liver fat fraction using magnetic resonance imaging (MRI) has become popular recently. One of the popular MRI methods to quantify liver fat fraction is the two-point Dixon method using in-phase (IP) and out-phase (OP) images. In this study we used a Dixon-based method and evaluated the difference between using individual correction factor calculated for each subject and an average correction factor. We also evaluated the accuracy of fat fraction calculation using a ROIs from a single slice versus multiple slices.