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Abstract #0855

In Vivo Characterization of Liver Fat Composition by 1H MR Spectroscopy

Gavin Hamilton1, Michael S. Middleton1, Takeshi Yokoo1, Lisa G. Clark1, Claude B. Sirlin1

1Department of Radiology, University of California, San Diego, San Diego, CA, United States

We examine the repeatability of liver triglyceride characterization by 1H MR Spectroscopy using a theoretical triglyceride model. Estimates of triglyceride unsaturation obtained from 1H MRS respiratory gated and free breathing acquisitions were compared. 1H MR Spectroscopy can repeatably measure the degree of liver fat unsaturation, and spectra collected with respiratory gating give a more repeatable characterization of liver fat composition than spectra collected with free breathing.