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Abstract #1036

7T Versus 3T Contrast-Enhanced Magnetic Resonance Imaging of Invasive Breast Cancer

Bertine Luus Stehouwer1, Dennis W. J. Klomp1, Mies A. Kortweg1, Peter R. Luijten1, Willem P. Th. M. Mali1, Maurice A. AJ. van Den Bosch1, Wouter B. Veldhuis1

1Radiology, UMCU, Utrecht, Netherlands

This abstract describes contrast-enhanced MR-imaging (DCE-MRI) of the breast at 7T, with 3T comparison and with 7T phantom B1-measuremnts, in a patient with ductulolobular carcinoma. 7T-DCE-MRI was done with a 3DT1-TFE sequence with selective water excitation (WATS), after injection of 0.1mmol/kg gadobutrol. 3T was performed according to standard protocol. The examinations were well tolerated. WATS resulted in good lesion-to-fat-and-fibroglandular-tissue contrast. Kinetic curves at both field strengths showed similar rapid initial-enhancement, followed by wash-out in the delayed phase for the most malignant curve. In conclusion, clinical 7T-DCE-MRI is technically feasible and may show enhancement kinetics amenable to standard BIRADS-interpretation.