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Abstract #1043

Diagnostic Performance of DCE-MR Imaging of the Breasts as a Function of Contrast Dose

Lawrence Dougherty1, Mark Alan Rosen1, Hee Kwon Song1, Mitchell D. Schnall1

1Radiology, Hospital of the University of Pennsylvania, Philadelphia, PA, United States

The effect of gadolimium contrast dose on the diagnostic performance of DCE-MR breast imaging was studied. A population of subjects with a suspicious breast mass received a MR examination using a high dose of contrast agent independent of weight (20 ml) and a second population received a low dose (0.1 mmol/kg). The diagnostic performance, assessed using tumor morphology as well as SER, was shown to increase with the higher dose.