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Abstract #1349

Rapid Cardiac T1 Mapping Within Two Heartbeats

Elodie Breton1,2, Daniel Kim1, Sohae Chung1, Leon Axel1

1Center for Biomedical Imaging - Radiology Research, New York University Langone Medical Center, New York, NY, United States; 2LSIIT - eAVR, University of Strasbourg, Strasbourg, France

Multi-point T1 mapping techniques, such as Modified Look-Locker inversion recovery (MOLLI), have shown quantitative changes in tissue T1 with ischemia but are sensitive to cardiac motion during data acquisition. In this work we developed a pixel-wise myocardial T1-mapping technique with reduced sensitivity to cardiac motion, adapted to perform pre-contrast and delayed-enhancement myocardial T1-mapping, with a 2-heartbeat-long acquisition. The proposed T1-mapping method was compared to a reference multi-point SR fitting method in 8 healthy volunteers before and after a gadolinium contrast injection. It was also performed in 2 patients with arrhythmia but no areas of delayed-enhanced was detected during routine contrast-enhanced clinical exam.