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Abstract #1374

Myocardial T1 Mapping at 3T using Variable Flip Angle Method: A Pilot Study

Hlne Poinsignon1,2, Maelene Lohezic2,3, Hai-Ling Margaret Cheng4,5, Pierre-Yves Marie6, Jacques Felblinger2,7, Marine Beaumont1,6

1CIT 801, INSERM, Nancy, France; 2IADI, Nancy-Universit, Nancy, France; 3Global Applied Science Laboratory., GE Healthcare, Nancy, France; 4Physiology & Experimental Medicine, The Hospital for Sick Children, Toronto, Ontario, Canada; 5Medical Biophysics, University of Toronto, Toronto, Ontario, Canada; 6CHU de Nancy, Nancy, France; 7U947, INSERM, Nancy, France

T1 mapping is a useful quantitative MR technique for cardiac tissue characterization and contrast agent concentration measurements. Because of cardiac and respiratory motion, cardiac T1 mapping remains challenging. The conventional modified look locker sequence allows myocardial T1 measurement, but it is a dedicated research sequence and T1 values are interpolated from apparent T1 values. In this work, we are interested in determining T1 using standard clinical sequences. This study aims at evaluating the feasibility of variable flip angle T1 mapping integrating B1 correction on the myocardium at 3T.