Christoffer Laustsen1,2, Steffen Ringaard1,
Mads Damkjr3, Michael Pedersen1
1Klinisk Institut, The MR Research
Centre, Aarhus University, Aarhus, Denmark; 2Danish Research
Centre for Magnetic Resonance, Hvidovre Hospital, Hvidovre, Denmark; 3Institute
of Molecular Medicine, University of Southern Denmark, Odense, Denmark
Sodium is a pivotal metabolite in the equilibrium cell state, and is therefore an ideal candidate as a biomarker for macroscopic damage, which is directly linked to the cellular alterations in the sodium gradient across the cell membrane. We here show the use of a simple relaxometry method for gaining additional insight in ex vivo organs. We show that it is possible to differentiate the healthy kidney from the diseased by 23Na-multi-component relaxation analysis.
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