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Abstract #1403

A Multi-Purpose Simulator of Coupled Spin Systems for MR Localized Spectroscopy & Spectroscopic Imaging

Zenon Starcuk Jr.1, Jana Starcukova1, Danielle Graveron-Demilly2

1Magnetic Resonance & Bioinformatics, Institute of Scientific Instruments, Academy of Sciences of the Czech Republic, Brno, Czech Republic; 2Creatis-LRMN, Universit Claude Bernard Lyon 1, France

The new simulator, implemented as a jMRUI plugin, addresses the needs of a practical spectroscopist as well as a pulse sequence physicist. Pulse sequences, optionally controlled by protocols, may include arbitrarily modulated RF and gradient pulses, cycles, overlapping pulses. Homo- or heteronuclear spin systems are described by spatial position, chemical shifts, J-coupling, and the Redfield relaxation matrix, whose parameters can be derived from simplified models (Solomon, component relaxivities of coherences). It can be used for the study of the effects of spectrally or spatially selective excitation, steady-state formation, magnetization transfer, pulse sequence optimization.