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Abstract #1404

The Classification of In Vivo Proton Magnetic Resonance Spectroscopy of Brain Abscesses using Principal Component Analysis (PCA)

Ssu-Ying Lu1, Cheng-Wen Ko, Tzu-Chao Chuang, Ping-Hong Lai2,3

1National Sun Yat-sen University, Kaohsiung, Taiwan; 2Veterans General Hospital-Kaohsiung; 3School of Medicine, National Yang-Ming University, Taipei, Taiwan

The interest in using proton MRS to identify the bacteria in pyogenic brain abscesses has been arising. In this study, we propose an algorithm using principal component analysis (PCA) to differentiate anaerobic and aerobic abscesses by means of in vivo short TE proton MR spectra. Our preliminary result shows PCA can be one potentially useful tool to distinguish various types of brain abscesses without any complicated post-processing algorithm. Our processing scheme may provide more precise analysis for MRS especially when macromolecular or strong lipid play an important role of clinical diagnosis.