Abstract #1443

Physiological Brain Temperature Change is Detectable by MRS

Yoshichika Yoshioka^1,2, Hiroshi Oikawa³, Yoshiyuki Kanbara⁴, Yutaka Matsumura⁴, Takashi Inoue⁵, Tsuyoshi Matsuda⁶, Akira Nabetani⁶, Junji Seki⁷

¹Immunology Frontier Research Center, Osaka University, Suita, Osaka, Japan; ²CREST, JST, Kawaguchi, Saitama, Japan; ³Radiology, Ninohe Haspital, Iwate, Japan; ⁴High Field MRI Research Institute, Iwate Medical University, Iwate, Japan; ⁵Neurosurgery, Kohnan Hospital, Sendai, Japan; ⁶GE Healthcare Japan Corp., Tokyo, Japan; ⁷National Cerebral & Cardiovascular Center Research Institute, Suita, Japan

We could detect the dynamic change of human brain temperature noninvasively using 1H-NMR spectroscopy. Our results show that the human brain temperature changes dynamically even at physiological conditions and by physiological tasks. Moreover the temperature change of human brain was larger than that of esophagus and axilla. This indicates that the brain temperature is affected easily by the blood flowing into the brain and also that the temperature of this blood is easily affected by foods and drinks. We can easily change the brain temperature of about 0.5 oC by drinking or light exercise.