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Abstract #1443

Physiological Brain Temperature Change is Detectable by MRS

Yoshichika Yoshioka1,2, Hiroshi Oikawa3, Yoshiyuki Kanbara4, Yutaka Matsumura4, Takashi Inoue5, Tsuyoshi Matsuda6, Akira Nabetani6, Junji Seki7

1Immunology Frontier Research Center, Osaka University, Suita, Osaka, Japan; 2CREST, JST, Kawaguchi, Saitama, Japan; 3Radiology, Ninohe Haspital, Iwate, Japan; 4High Field MRI Research Institute, Iwate Medical University, Iwate, Japan; 5Neurosurgery, Kohnan Hospital, Sendai, Japan; 6GE Healthcare Japan Corp., Tokyo, Japan; 7National Cerebral & Cardiovascular Center Research Institute, Suita, Japan


We could detect the dynamic change of human brain temperature noninvasively using 1H-NMR spectroscopy. Our results show that the human brain temperature changes dynamically even at physiological conditions and by physiological tasks. Moreover the temperature change of human brain was larger than that of esophagus and axilla. This indicates that the brain temperature is affected easily by the blood flowing into the brain and also that the temperature of this blood is easily affected by foods and drinks. We can easily change the brain temperature of about 0.5 oC by drinking or light exercise.