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Abstract #1477

Prostate MRE at 3T: Trans-Perineal Wave Propagation

Ramin Sebastian Sahebjavaher1, Ali Baghani1, Ralph Sinkus2, Septimiu E. Salcudean1

1Electrical & Computer Engineering, University of British Columbia, Vancouver, British Columbia, Canada; 2Laboratoire Ondes et Acoustique, ESPCI, Paris, France

The diagnostic importance of elasticity for prostate cancer is well established; therefore, viscoelastic information acquired from in-vivo prostatic tissue using MR Elastography (MRE) is expected to provide valuable clinical information. A second harmonic MRE approach was performed on healthy subjects in supine position with the transducer applied at the perineum. Initial results show that the waves sufficiently penetrate into the prostate. Applying the mechanical excitation to the perineum is comfortable for the patients even for extended imaging examinations. The reconstructed viscoelastic values visually show a significant correspondence to the anatomy. This study shows that trans-perineal 2nd harmonic MRE is feasible.