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Abstract #1492

Intracellular Volume Fraction Measurements using Single Quantum Sodium MRI.

Lazar Fleysher1, Donatello Arienzo1,2, Niels Oesingmann3, Matilde Inglese1,4

1Radiology, NYU School of Medicine, New York, United States; 2Biobehavioral SCI, UCLA, United States; 3Siemens Medical Solutions USA, Malvern, PA, United States; 4Neurology, NYU School of Medicine, New York, United States

In this work we present a method based on sodium MRI which is capable of assessing intracellular sodium volume fraction (ISVF) in-vivo. We find that ISVFGM=815 % and ISVFWM = 912% which is in a good agreement with previous invasive studies.