Rupeng Li1, Phillip Bishop, Andrzej Jesmanowicz, Andrew Nencka, J. B. Stephenson IV2, Christopher Pawela, Ji-Geng Yan2, Anthony G. Hudetz3, Hani Matloub2, James S. Hyde1
1Biophysics, Medical College of Wisconsin, Milwaukee, WI, United States; 2Plastic Surgery, Medical College of Wisconsin; 3Anesthesiology, Medical College of Wisconsin
A more-sensitive approach to whole-brain acquisition of the rat is showed here. It consists of an array of coils on the upper surface in combination with intra-oral coils supported on a bite bar. The intra-oral coil is customized with the coil surface directly contacted to the upper palate. This novel coil array design voids the tissue interference from the side and the bottom of the rat brain, and minimizes the signal drop off. This two coil array also causes apparent improvement in the SNR. This design could also be used for other small animal studies.