Abstract #2054

Feasibility of Dynamic Contrast Enhanced MRI in Oral Cavity Cancer: A Comparison Between Reference Region Model, General Kinetic Model & Pathological Grading

Shy-Chyi Chin¹, Yeng-Peng Liao², Ya-Ting Chuang¹, Ho-Ling Liu²

¹Department of Nedical Imaging & Intervention, Chang-Gung Medical Center, Guei-Shan, Tao-Yuan, Taiwan; ²Chang Gung University, Department of Medical Imaging & Radiological Sciences, Guei-Shan, Tao-Yuan, Taiwan

We concluded that the ideal application of the dynamic contrast-enhanced MRI (DCE-MRI) technique can be achieved in the clinical oncology even in patients with suboptimal scanning condition like oral cavity malignancy with inevitable head motion and image distortion. Most of the imaging distortion can be overcome by using the alternate DCE-MRI method, that is, reference region model (RRM) to substitute with the conventional general kinetic model (GKM). On the other hand, DCE-MRI derived parameters are not correlative to pathological grading, though. The more sophisticated analysis between these parameters deserves further investigation.