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Abstract #2150

Ischemic Brain Damage & Loss of Ion Homeostasis During Focal Ischemia

Fernando Emilio Boada1, Edwin Nemoto2, Yongxian Qian3, Costin Tanase3, Charles Jungreis4, Jonathan Weimer, Vincent Lee

1Radiology & Bioengineering, University of Pittsburgh, Pittsburgh, PA, United States; 2Neurosurgery, University of New Mexico, Albuquerque, NM, United States; 3Radiology, University of Pittsburgh, Pittsburgh, PA, United States; 4Radiology, Temple University, Philadelphia, PA, United States


In this paper we use a non-human primate model of reversible focal ischemia to present evidence that elevated tissue sodium concentration (>65mM) during focal cerebral ischemia increases the risk of infarction after tissue reperfusion.

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