Fernando Emilio Boada1, Edwin Nemoto2,
Yongxian Qian3, Costin Tanase3, Charles Jungreis4,
Jonathan Weimer, Vincent Lee
1Radiology &
Bioengineering, University of Pittsburgh, Pittsburgh, PA, United States; 2Neurosurgery,
University of New Mexico, Albuquerque, NM, United States; 3Radiology,
University of Pittsburgh, Pittsburgh, PA, United States; 4Radiology,
Temple University, Philadelphia, PA, United States
In this paper we use a non-human primate model of reversible focal ischemia to present evidence that elevated tissue sodium concentration (>65mM) during focal cerebral ischemia increases the risk of infarction after tissue reperfusion.