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Abstract #2283

Anatomical Phenotyping of the PML Knockout Mouse

Benjamin Sinclair1,2, Jon Cleary2, Joanne Henderson3, Marc Modat1, Francesca Norris2,4, Paolo Salomoni3, Sebastien Ourselin1, Mark Lythgoe2

1Centre for Medical Image Computing, UCL, London, United Kingdom; 2Centre for Advanced Biomedical Imaging, UCL, London, United Kingdom; 3UCL Cancer Institute, London, United Kingdom; 4Centre for Mathematics & Physics in the Life Sciences & EXperimental Biology (CoMPLEX)

This study applies MRI and image processing techniques to a mouse model with a knockout of the PML gene, which has known links with tumour suppression and neurogenisis.