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Abstract #2323

Robust Subdivision of the Thalamus in Children Based on Probability-Distribution-Functions Calculated from Probabilistic Tractography.

Philip Julian Broser1, Faraneh Vargha-Khadem2, Chris A. Clark1

1Imaging & Biophysics Unit, UCL Institute of Child Health, London, United Kingdom; 2Developmental Cognitive Neuroscience Unit,, UCL Institute of Child Health

In this study we developed a new method to analyze the thalamus and its constituent substructures based on probabilistic tractography. Probabilistic tractography is an MRI technique that estimates the likelihood of connection between two points in the brain by sampling the distribution of greatest diffusion directions in each voxel of the brain image. In contrast to the previously published methods, which are applied at the group level, our method can be used to analyze the thalamic substructures in individual datasets.