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Abstract #2437

DWI of Head & Neck Cancer the Effect of B Values on ADC Measurements

Kwok Keung Chow1, David Ka Wai Yeung1, Queenie Chan2, Ann D. King1

1Department of Imaging & Interventional Radiology, The Chinese University of Hong Kong, Hong Kong, Hong Kong; 2Philips Healthcare

The aim of this study was to examine the effect of b-values on ADC measurement of cancer in a group of patients with nasopharyngeal carcinoma (NPC). Two sets of b-values [(a) 0, 100, 200, 300, 400 and 500 s/mm2; (b) 0, 200, 400, 600, 800 and 1000 s/mm2] DWI was performed on 14 patients with histologically confirmed NPC. ADC maps were calculated using two and six b-factors. The ADC values using high b-values (1000 s/mm2) were significantly lower to the low b-value (500 s/mm2). There are no significant differences when using two b-factor or six b-factor calculation method.