Marshall S. Sussman1, Walter Kucharczyk1
1Medical Imaging,
University Health Network,
Measurement of a tissues T2 spectrum provides information beyond that of methods used in current clinical practice. However, T2 spectrum analysis is rarely used clinically. This is because the current method used to measure T2 spectra, multi-exponential fitting, requires very long scan times. An alternate method for assessing T2 spectra is linear combination filtering (LCF). LCF can be performed in clinically reasonable scan times. However, it only assesses a single, extended region of the T2 spectrum. In this project, we develop a novel LCF technique that provides an estimate of the full T2 spectrum in a clinically reasonable scan time.
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