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Abstract #2784

Analysis of Magnetization Transfer Ratio Measurements at 3T using Multiple-Acquisition Balanced SSFP

Monika Gloor1, Klaus Scheffler1, Oliver Bieri1

1Radiological Physics, University of Basel Hospital, Basel, Switzerland

Recently, it has been shown that fast magnetization transfer (MT) scans based on balanced steady-state free precession (bSSFP) with RF pulse modification achieve high SNR and high reproducibility at 1.5T. At 3T, combination of multiple, phase-cycled, bSSFP scans might be required to overcome limitations from off-resonance artifacts. In this study, different recombination methods for the generation of accurate magnetization transfer ratio (MTR) maps were analyzed. Maximum intensity projection removes off-resonance artifacts without significant MTR modification, whereas sum-of-squares and weighted-combination bSSFP yield reduced MTR values.