Abstract #2788

Influence of Magnetisation Transfer on Established T1 Mapping Methods

Miriam Rabea Kubach¹, Kaveh Vahedipour², Tony Stoecker², N. Jon Shah^2,3

¹Forschungszentrum Juelich, Institute of Neuroscience and Medicine , Juelich, NRW, Germany; ²Forschungszentrum Juelich, Institute of Neuroscience & Medicine, Juelich, NRW, Germany; ³Department of Neurology, Faculty of Medicine, JARA, RWTH Aachen University, Aachen, Germany

Precise and accurate T1 mapping in the presence of MT requires modifications of the fitting model to account for the exchange. If those are neglected and the standard models are applied, an error in the T1 values is inevitable. Our work aims to quantify this error for different T1 mapping methods based on simulations of white and grey matter. The effects of SNR and MT on the precision and accuracy of T1 mapping was studied.