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Abstract #2912

B1+-Insensitive Slice-Selective Pulses Constructed from Optimized Non-Selective Composite Waveforms

Jay Moore1,2, Marcin Jankiewicz1,3, Adam W Anderson1,4, John C. Gore1,4

1Institute of Imaging Science, Vanderbilt University, Nashville, TN, United States; 2Physics & Astronomy, Vanderbilt University, Nashville, TN, United States; 3Department of Radiology & Radiological Sciences, Vanderbilt University; 4Department of Biomedical Engineering, Vanderbilt University

Non-selective composite RF pulses are numerically optimized for insensitivity to static and RF field variations and subsequently transformed into slice-selective pulses via RF shape modification and execution of an oscillating gradient waveform. Pulse designs accommodate the gradient performance and maximum RF amplitude limits of a commercial 7 T human scanner while significantly reducing signal variations due to B1+ inhomogeneities in the human brain.