Clinical Significance of Lipid Peak in In-Vivo 1H-MR Spectroscopy of Ovarian Thecomas/Fibrothecomas

Mayumi Takeuchi¹, Kenji Matsuzaki¹, Masafumi Harada¹

We evaluated 7 ovarian thecomas/fibrothecomas, 6 other benign ovarian solid tumors (2 fibromas, 3 adenofibromas and 1 fibromatosis), and 7 subserosal leiomyomas by 1H-MR spectroscopy at 3T. All lesions showed totally or partially low signal intensity on T2-weighted images. High lipid peaks were observed in all 7 thecomas/fibrothecomas reflecting intracellular lipids, whereas low lipid peaks were observed in only one fibroma of 6 ovarian tumors. None of all 7 leiomyomas showed lipid peak. The presence of high lipid peak may be specific for thecomas/fibrothecomas and useful for the differential diagnosis of gynecologic tumors exhibiting low signal intensity on T2-weighted images.