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Abstract #3000

MRI Detection of Glycogen In Vivo in Diabetic Mice at 3 Tesla: Feasibility & Initial Experience

Mina Kim1, Queenie Chan1,2, James Y. B. Lau3, Sookja K. Chung3, Pek-Lan Khong1

1Departement of Diagnostic Radiology, the University of Hong Kong, Hong Kong, Pokfulam, Hong Kong; 2Philips Healthcare, Hong Kong; 3Department of Anatomy, the University of Hong Kong

Development of sensitive method to quantify glycogen in vivo may help to understand the pathophysiology of type-2 diabetes. In present study, we tested feasibility of in vivo glycogen detection in diabetic mouse model using chemical exchange saturation transfer imaging. Our results suggest that in vivo CEST quantification in mouse liver is feasible in a clinical scanner.